HL7® FHIR® Te Aho o Te Kahu, Cancer Control Agency Implementation Guide
0.1.0 - CI Build

HL7® FHIR® Te Aho o Te Kahu, Cancer Control Agency Implementation Guide, published by Te Aho o Te Kahu, Cancer Control Agency. This guide is not an authorized publication; it is the continuous build for version 0.1.0 built by the FHIR (HL7® FHIR® Standard) CI Build. This version is based on the current content of https://github.com/HL7NZ/cca/ and changes regularly. See the Directory of published versions

## : LUNG NSCLC NON-Metastatic - alectinib - XML Representation

Active as of 2026-05-21

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    <PlanDefinition xmlns="http://hl7.org/fhir">
      <id value="52401000210103"/>
      <meta>
        <profile
                 value="http://hl7.org.nz/fhir/StructureDefinition/CcaPlanDefinition"/>
      </meta>
      <text>
        <status value="extensions"/>
        <div xmlns="http://www.w3.org/1999/xhtml" class="regimen-display">

            <h1 title="Respiratory Non small cell lung cancer NON-Metastatic - alectinib">LUNG NSCLC NON-Metastatic - alectinib</h1>

            <ul class="regimen-tabs">
            </ul>

            <div>
                <div class="regimen-tab-content overview-content active">
                    <h2 class="regimen-section-title">Treatment Overview</h2>

                    <div>
                        <div id="overview-content|bfe31f90-10e9-4d90-80a2-5aeccec14939" title="Cycle 1" class="cycle-overview regimen-item">
                            <h2>
                                Cycle 1 (and all further cycles) - 28 days
                            </h2>
                            <div class="regimen-row">
                                <div class="regimen-col-3"><b>Cycle length:</b></div>
                                <div class="regimen-col-9">28</div>
                            </div>

                        </div>
                    </div>
                </div>
                <div class="regimen-tab-content cycle-details-content">
                    <h2 class="regimen-section-title">Cycle details</h2>
                        <div class="cycle-overview">
                            <h2>
                                Cycle 1 (and all further cycles) - 28 days
                            </h2>
                            <table>
                                <thead>
                                    <tr>
                                        <th class="regimen-col-3">Medication</th>
                                        <th class="regimen-col-2">Dose</th>
                                        <th class="regimen-col-3">Route</th>
                                        <th class="regimen-col-2">Days</th>
                                        <th class="regimen-col-2">Max Duration</th>
                                    </tr>
                                </thead>
                                <tbody>
                                        <tr id="cycle-details-content|Order-Set-1-1f2b1a9a-5571-40c4-8d62-90a4adb8d23b" title="Cycle 1: alectinib" class="regimen-item">
                                            <td class="regimen-col-3">
                                                <span title="46490541000116100" class="medication">alectinib</span>
                                            </td>
                                            <td class="regimen-col-2 handle-lines">600 mg flat Twice daily</td>
                                            <td class="regimen-col-3">oral administration</td>
                                            <td class="regimen-col-2">1 to 28</td>
                                            <td class="regimen-col-2 handle-lines"/>
                                        </tr>
                                        <tr id="cycle-details-content|Order-Set-2-575cba16-7209-450d-b0f9-f2ee88fa836f" title="Cycle 1: loperamide" class="regimen-item">
                                            <td class="regimen-col-3">
                                                <span title="10056821000116103" class="medication">loperamide</span>
                                            </td>
                                            <td class="regimen-col-2 handle-lines">2 mg flat</td>
                                            <td class="regimen-col-3">oral administration</td>
                                            <td class="regimen-col-2">1</td>
                                            <td class="regimen-col-2 handle-lines"/>
                                        </tr>
                                        <tr id="cycle-details-content|Order-Set-3-151557f3-587a-42b2-9385-8e9246151476" title="Cycle 1: domperidone" class="regimen-item">
                                            <td class="regimen-col-3">
                                                <span title="10472211000116103" class="medication">domperidone</span>
                                            </td>
                                            <td class="regimen-col-2 handle-lines">10 mg flat Three times daily</td>
                                            <td class="regimen-col-3">oral administration</td>
                                            <td class="regimen-col-2">1</td>
                                            <td class="regimen-col-2 handle-lines"/>
                                        </tr>
                                </tbody>
                            </table>
                        </div>
                </div>
                <div class="regimen-tab-content day-details-content">
                    <h2 class="regimen-section-title">Full details</h2>
                        <div class="cycle">
                            <h2>
                                Cycle 1 (and all further cycles) - 28 days
                            </h2>
                            <div>

                                    <div class="day-overview">
                                        <h3>Day: 1</h3>
                                        <table>
                                            <tr>
                                                <th class="regimen-col-2">Medication</th>
                                                <th class="regimen-col-2">Dose</th>
                                                <th class="regimen-col-2">Route</th>
                                                <th class="regimen-col-2">Max duration</th>
                                                <th class="regimen-col-4">Details</th>
                                            </tr>
                                                <tr id="day-details-content|bfe31f90-10e9-4d90-80a2-5aeccec14939-1-1f2b1a9a-5571-40c4-8d62-90a4adb8d23b" title="Cycle 1: alectinib - Day 1" class="regimen-item">
                                                    <td class="regimen-col-2">
                                                        <span title="46490541000116100" class="medication">alectinib</span>
                                                    </td>
                                                    <td class="regimen-col-2 handle-lines">600 mg flat Twice daily</td>
                                                    <td class="regimen-col-2">oral administration</td>
                                                    <td class="regimen-col-2 handle-lines"/>
                                                    <td class="regimen-col-4">
                                                            <div class="regimen-instructions html-instructions"><b>Instructions:</b><br/>Take with food. Swallow whole, do not crush or chew. Protect yourself from too much natural or artificial sunlight while being treated with this medicine.</div>
                                                    </td>
                                                </tr>
                                                <tr id="day-details-content|bfe31f90-10e9-4d90-80a2-5aeccec14939-1-575cba16-7209-450d-b0f9-f2ee88fa836f" title="Cycle 1: loperamide - Day 1" class="regimen-item">
                                                    <td class="regimen-col-2">
                                                        <span title="10056821000116103" class="medication">loperamide</span>
                                                    </td>
                                                    <td class="regimen-col-2 handle-lines">2 mg flat</td>
                                                    <td class="regimen-col-2">oral administration</td>
                                                    <td class="regimen-col-2 handle-lines"/>
                                                    <td class="regimen-col-4">
                                                            <div class="regimen-instructions html-instructions"><b>Instructions:</b><br/>Take TWO capsules (=4 mg) at onset of loose bowel motions and a further ONE capsule (=2 mg) for every loose bowel motion (maximum of EIGHT capsules in 24 hours), or use as directed by oncologist or haematologist. </div>
                                                    </td>
                                                </tr>
                                                <tr id="day-details-content|bfe31f90-10e9-4d90-80a2-5aeccec14939-1-151557f3-587a-42b2-9385-8e9246151476" title="Cycle 1: domperidone - Day 1" class="regimen-item">
                                                    <td class="regimen-col-2">
                                                        <span title="10472211000116103" class="medication">domperidone</span>
                                                    </td>
                                                    <td class="regimen-col-2 handle-lines">10 mg flat Three times daily</td>
                                                    <td class="regimen-col-2">oral administration</td>
                                                    <td class="regimen-col-2 handle-lines"/>
                                                    <td class="regimen-col-4">
                                                            <div class="regimen-instructions html-instructions"><b>Instructions:</b><br/>When required for nausea and/or vomiting.</div>
                                                    </td>
                                                </tr>
                                        </table>
                                    </div>
                                    <div class="day-overview">
                                        <h3>Day: 2</h3>
                                        <table>
                                            <tr>
                                                <th class="regimen-col-2">Medication</th>
                                                <th class="regimen-col-2">Dose</th>
                                                <th class="regimen-col-2">Route</th>
                                                <th class="regimen-col-2">Max duration</th>
                                                <th class="regimen-col-4">Details</th>
                                            </tr>
                                                <tr id="day-details-content|bfe31f90-10e9-4d90-80a2-5aeccec14939-2-1f2b1a9a-5571-40c4-8d62-90a4adb8d23b" title="Cycle 1: alectinib - Day 2" class="regimen-item">
                                                    <td class="regimen-col-2">
                                                        <span title="46490541000116100" class="medication">alectinib</span>
                                                    </td>
                                                    <td class="regimen-col-2 handle-lines">600 mg flat Twice daily</td>
                                                    <td class="regimen-col-2">oral administration</td>
                                                    <td class="regimen-col-2 handle-lines"/>
                                                    <td class="regimen-col-4">
                                                            <div class="regimen-instructions html-instructions"><b>Instructions:</b><br/>Take with food. Swallow whole, do not crush or chew. Protect yourself from too much natural or artificial sunlight while being treated with this medicine.</div>
                                                    </td>
                                                </tr>
                                        </table>
                                    </div>
                                    <div class="day-overview">
                                        <h3>Day: 3</h3>
                                        <table>
                                            <tr>
                                                <th class="regimen-col-2">Medication</th>
                                                <th class="regimen-col-2">Dose</th>
                                                <th class="regimen-col-2">Route</th>
                                                <th class="regimen-col-2">Max duration</th>
                                                <th class="regimen-col-4">Details</th>
                                            </tr>
                                                <tr id="day-details-content|bfe31f90-10e9-4d90-80a2-5aeccec14939-3-1f2b1a9a-5571-40c4-8d62-90a4adb8d23b" title="Cycle 1: alectinib - Day 3" class="regimen-item">
                                                    <td class="regimen-col-2">
                                                        <span title="46490541000116100" class="medication">alectinib</span>
                                                    </td>
                                                    <td class="regimen-col-2 handle-lines">600 mg flat Twice daily</td>
                                                    <td class="regimen-col-2">oral administration</td>
                                                    <td class="regimen-col-2 handle-lines"/>
                                                    <td class="regimen-col-4">
                                                            <div class="regimen-instructions html-instructions"><b>Instructions:</b><br/>Take with food. Swallow whole, do not crush or chew. Protect yourself from too much natural or artificial sunlight while being treated with this medicine.</div>
                                                    </td>
                                                </tr>
                                        </table>
                                    </div>
                                    <div class="day-overview">
                                        <h3>Day: 4</h3>
                                        <table>
                                            <tr>
                                                <th class="regimen-col-2">Medication</th>
                                                <th class="regimen-col-2">Dose</th>
                                                <th class="regimen-col-2">Route</th>
                                                <th class="regimen-col-2">Max duration</th>
                                                <th class="regimen-col-4">Details</th>
                                            </tr>
                                                <tr id="day-details-content|bfe31f90-10e9-4d90-80a2-5aeccec14939-4-1f2b1a9a-5571-40c4-8d62-90a4adb8d23b" title="Cycle 1: alectinib - Day 4" class="regimen-item">
                                                    <td class="regimen-col-2">
                                                        <span title="46490541000116100" class="medication">alectinib</span>
                                                    </td>
                                                    <td class="regimen-col-2 handle-lines">600 mg flat Twice daily</td>
                                                    <td class="regimen-col-2">oral administration</td>
                                                    <td class="regimen-col-2 handle-lines"/>
                                                    <td class="regimen-col-4">
                                                            <div class="regimen-instructions html-instructions"><b>Instructions:</b><br/>Take with food. Swallow whole, do not crush or chew. Protect yourself from too much natural or artificial sunlight while being treated with this medicine.</div>
                                                    </td>
                                                </tr>
                                        </table>
                                    </div>
                                    <div class="day-overview">
                                        <h3>Day: 5</h3>
                                        <table>
                                            <tr>
                                                <th class="regimen-col-2">Medication</th>
                                                <th class="regimen-col-2">Dose</th>
                                                <th class="regimen-col-2">Route</th>
                                                <th class="regimen-col-2">Max duration</th>
                                                <th class="regimen-col-4">Details</th>
                                            </tr>
                                                <tr id="day-details-content|bfe31f90-10e9-4d90-80a2-5aeccec14939-5-1f2b1a9a-5571-40c4-8d62-90a4adb8d23b" title="Cycle 1: alectinib - Day 5" class="regimen-item">
                                                    <td class="regimen-col-2">
                                                        <span title="46490541000116100" class="medication">alectinib</span>
                                                    </td>
                                                    <td class="regimen-col-2 handle-lines">600 mg flat Twice daily</td>
                                                    <td class="regimen-col-2">oral administration</td>
                                                    <td class="regimen-col-2 handle-lines"/>
                                                    <td class="regimen-col-4">
                                                            <div class="regimen-instructions html-instructions"><b>Instructions:</b><br/>Take with food. Swallow whole, do not crush or chew. Protect yourself from too much natural or artificial sunlight while being treated with this medicine.</div>
                                                    </td>
                                                </tr>
                                        </table>
                                    </div>
                                    <div class="day-overview">
                                        <h3>Day: 6</h3>
                                        <table>
                                            <tr>
                                                <th class="regimen-col-2">Medication</th>
                                                <th class="regimen-col-2">Dose</th>
                                                <th class="regimen-col-2">Route</th>
                                                <th class="regimen-col-2">Max duration</th>
                                                <th class="regimen-col-4">Details</th>
                                            </tr>
                                                <tr id="day-details-content|bfe31f90-10e9-4d90-80a2-5aeccec14939-6-1f2b1a9a-5571-40c4-8d62-90a4adb8d23b" title="Cycle 1: alectinib - Day 6" class="regimen-item">
                                                    <td class="regimen-col-2">
                                                        <span title="46490541000116100" class="medication">alectinib</span>
                                                    </td>
                                                    <td class="regimen-col-2 handle-lines">600 mg flat Twice daily</td>
                                                    <td class="regimen-col-2">oral administration</td>
                                                    <td class="regimen-col-2 handle-lines"/>
                                                    <td class="regimen-col-4">
                                                            <div class="regimen-instructions html-instructions"><b>Instructions:</b><br/>Take with food. Swallow whole, do not crush or chew. Protect yourself from too much natural or artificial sunlight while being treated with this medicine.</div>
                                                    </td>
                                                </tr>
                                        </table>
                                    </div>
                                    <div class="day-overview">
                                        <h3>Day: 7</h3>
                                        <table>
                                            <tr>
                                                <th class="regimen-col-2">Medication</th>
                                                <th class="regimen-col-2">Dose</th>
                                                <th class="regimen-col-2">Route</th>
                                                <th class="regimen-col-2">Max duration</th>
                                                <th class="regimen-col-4">Details</th>
                                            </tr>
                                                <tr id="day-details-content|bfe31f90-10e9-4d90-80a2-5aeccec14939-7-1f2b1a9a-5571-40c4-8d62-90a4adb8d23b" title="Cycle 1: alectinib - Day 7" class="regimen-item">
                                                    <td class="regimen-col-2">
                                                        <span title="46490541000116100" class="medication">alectinib</span>
                                                    </td>
                                                    <td class="regimen-col-2 handle-lines">600 mg flat Twice daily</td>
                                                    <td class="regimen-col-2">oral administration</td>
                                                    <td class="regimen-col-2 handle-lines"/>
                                                    <td class="regimen-col-4">
                                                            <div class="regimen-instructions html-instructions"><b>Instructions:</b><br/>Take with food. Swallow whole, do not crush or chew. Protect yourself from too much natural or artificial sunlight while being treated with this medicine.</div>
                                                    </td>
                                                </tr>
                                        </table>
                                    </div>
                                    <div class="day-overview">
                                        <h3>Day: 8</h3>
                                        <table>
                                            <tr>
                                                <th class="regimen-col-2">Medication</th>
                                                <th class="regimen-col-2">Dose</th>
                                                <th class="regimen-col-2">Route</th>
                                                <th class="regimen-col-2">Max duration</th>
                                                <th class="regimen-col-4">Details</th>
                                            </tr>
                                                <tr id="day-details-content|bfe31f90-10e9-4d90-80a2-5aeccec14939-8-1f2b1a9a-5571-40c4-8d62-90a4adb8d23b" title="Cycle 1: alectinib - Day 8" class="regimen-item">
                                                    <td class="regimen-col-2">
                                                        <span title="46490541000116100" class="medication">alectinib</span>
                                                    </td>
                                                    <td class="regimen-col-2 handle-lines">600 mg flat Twice daily</td>
                                                    <td class="regimen-col-2">oral administration</td>
                                                    <td class="regimen-col-2 handle-lines"/>
                                                    <td class="regimen-col-4">
                                                            <div class="regimen-instructions html-instructions"><b>Instructions:</b><br/>Take with food. Swallow whole, do not crush or chew. Protect yourself from too much natural or artificial sunlight while being treated with this medicine.</div>
                                                    </td>
                                                </tr>
                                        </table>
                                    </div>
                                    <div class="day-overview">
                                        <h3>Day: 9</h3>
                                        <table>
                                            <tr>
                                                <th class="regimen-col-2">Medication</th>
                                                <th class="regimen-col-2">Dose</th>
                                                <th class="regimen-col-2">Route</th>
                                                <th class="regimen-col-2">Max duration</th>
                                                <th class="regimen-col-4">Details</th>
                                            </tr>
                                                <tr id="day-details-content|bfe31f90-10e9-4d90-80a2-5aeccec14939-9-1f2b1a9a-5571-40c4-8d62-90a4adb8d23b" title="Cycle 1: alectinib - Day 9" class="regimen-item">
                                                    <td class="regimen-col-2">
                                                        <span title="46490541000116100" class="medication">alectinib</span>
                                                    </td>
                                                    <td class="regimen-col-2 handle-lines">600 mg flat Twice daily</td>
                                                    <td class="regimen-col-2">oral administration</td>
                                                    <td class="regimen-col-2 handle-lines"/>
                                                    <td class="regimen-col-4">
                                                            <div class="regimen-instructions html-instructions"><b>Instructions:</b><br/>Take with food. Swallow whole, do not crush or chew. Protect yourself from too much natural or artificial sunlight while being treated with this medicine.</div>
                                                    </td>
                                                </tr>
                                        </table>
                                    </div>
                                    <div class="day-overview">
                                        <h3>Day: 10</h3>
                                        <table>
                                            <tr>
                                                <th class="regimen-col-2">Medication</th>
                                                <th class="regimen-col-2">Dose</th>
                                                <th class="regimen-col-2">Route</th>
                                                <th class="regimen-col-2">Max duration</th>
                                                <th class="regimen-col-4">Details</th>
                                            </tr>
                                                <tr id="day-details-content|bfe31f90-10e9-4d90-80a2-5aeccec14939-10-1f2b1a9a-5571-40c4-8d62-90a4adb8d23b" title="Cycle 1: alectinib - Day 10" class="regimen-item">
                                                    <td class="regimen-col-2">
                                                        <span title="46490541000116100" class="medication">alectinib</span>
                                                    </td>
                                                    <td class="regimen-col-2 handle-lines">600 mg flat Twice daily</td>
                                                    <td class="regimen-col-2">oral administration</td>
                                                    <td class="regimen-col-2 handle-lines"/>
                                                    <td class="regimen-col-4">
                                                            <div class="regimen-instructions html-instructions"><b>Instructions:</b><br/>Take with food. Swallow whole, do not crush or chew. Protect yourself from too much natural or artificial sunlight while being treated with this medicine.</div>
                                                    </td>
                                                </tr>
                                        </table>
                                    </div>
                                    <div class="day-overview">
                                        <h3>Day: 11</h3>
                                        <table>
                                            <tr>
                                                <th class="regimen-col-2">Medication</th>
                                                <th class="regimen-col-2">Dose</th>
                                                <th class="regimen-col-2">Route</th>
                                                <th class="regimen-col-2">Max duration</th>
                                                <th class="regimen-col-4">Details</th>
                                            </tr>
                                                <tr id="day-details-content|bfe31f90-10e9-4d90-80a2-5aeccec14939-11-1f2b1a9a-5571-40c4-8d62-90a4adb8d23b" title="Cycle 1: alectinib - Day 11" class="regimen-item">
                                                    <td class="regimen-col-2">
                                                        <span title="46490541000116100" class="medication">alectinib</span>
                                                    </td>
                                                    <td class="regimen-col-2 handle-lines">600 mg flat Twice daily</td>
                                                    <td class="regimen-col-2">oral administration</td>
                                                    <td class="regimen-col-2 handle-lines"/>
                                                    <td class="regimen-col-4">
                                                            <div class="regimen-instructions html-instructions"><b>Instructions:</b><br/>Take with food. Swallow whole, do not crush or chew. Protect yourself from too much natural or artificial sunlight while being treated with this medicine.</div>
                                                    </td>
                                                </tr>
                                        </table>
                                    </div>
                                    <div class="day-overview">
                                        <h3>Day: 12</h3>
                                        <table>
                                            <tr>
                                                <th class="regimen-col-2">Medication</th>
                                                <th class="regimen-col-2">Dose</th>
                                                <th class="regimen-col-2">Route</th>
                                                <th class="regimen-col-2">Max duration</th>
                                                <th class="regimen-col-4">Details</th>
                                            </tr>
                                                <tr id="day-details-content|bfe31f90-10e9-4d90-80a2-5aeccec14939-12-1f2b1a9a-5571-40c4-8d62-90a4adb8d23b" title="Cycle 1: alectinib - Day 12" class="regimen-item">
                                                    <td class="regimen-col-2">
                                                        <span title="46490541000116100" class="medication">alectinib</span>
                                                    </td>
                                                    <td class="regimen-col-2 handle-lines">600 mg flat Twice daily</td>
                                                    <td class="regimen-col-2">oral administration</td>
                                                    <td class="regimen-col-2 handle-lines"/>
                                                    <td class="regimen-col-4">
                                                            <div class="regimen-instructions html-instructions"><b>Instructions:</b><br/>Take with food. Swallow whole, do not crush or chew. Protect yourself from too much natural or artificial sunlight while being treated with this medicine.</div>
                                                    </td>
                                                </tr>
                                        </table>
                                    </div>
                                    <div class="day-overview">
                                        <h3>Day: 13</h3>
                                        <table>
                                            <tr>
                                                <th class="regimen-col-2">Medication</th>
                                                <th class="regimen-col-2">Dose</th>
                                                <th class="regimen-col-2">Route</th>
                                                <th class="regimen-col-2">Max duration</th>
                                                <th class="regimen-col-4">Details</th>
                                            </tr>
                                                <tr id="day-details-content|bfe31f90-10e9-4d90-80a2-5aeccec14939-13-1f2b1a9a-5571-40c4-8d62-90a4adb8d23b" title="Cycle 1: alectinib - Day 13" class="regimen-item">
                                                    <td class="regimen-col-2">
                                                        <span title="46490541000116100" class="medication">alectinib</span>
                                                    </td>
                                                    <td class="regimen-col-2 handle-lines">600 mg flat Twice daily</td>
                                                    <td class="regimen-col-2">oral administration</td>
                                                    <td class="regimen-col-2 handle-lines"/>
                                                    <td class="regimen-col-4">
                                                            <div class="regimen-instructions html-instructions"><b>Instructions:</b><br/>Take with food. Swallow whole, do not crush or chew. Protect yourself from too much natural or artificial sunlight while being treated with this medicine.</div>
                                                    </td>
                                                </tr>
                                        </table>
                                    </div>
                                    <div class="day-overview">
                                        <h3>Day: 14</h3>
                                        <table>
                                            <tr>
                                                <th class="regimen-col-2">Medication</th>
                                                <th class="regimen-col-2">Dose</th>
                                                <th class="regimen-col-2">Route</th>
                                                <th class="regimen-col-2">Max duration</th>
                                                <th class="regimen-col-4">Details</th>
                                            </tr>
                                                <tr id="day-details-content|bfe31f90-10e9-4d90-80a2-5aeccec14939-14-1f2b1a9a-5571-40c4-8d62-90a4adb8d23b" title="Cycle 1: alectinib - Day 14" class="regimen-item">
                                                    <td class="regimen-col-2">
                                                        <span title="46490541000116100" class="medication">alectinib</span>
                                                    </td>
                                                    <td class="regimen-col-2 handle-lines">600 mg flat Twice daily</td>
                                                    <td class="regimen-col-2">oral administration</td>
                                                    <td class="regimen-col-2 handle-lines"/>
                                                    <td class="regimen-col-4">
                                                            <div class="regimen-instructions html-instructions"><b>Instructions:</b><br/>Take with food. Swallow whole, do not crush or chew. Protect yourself from too much natural or artificial sunlight while being treated with this medicine.</div>
                                                    </td>
                                                </tr>
                                        </table>
                                    </div>
                                    <div class="day-overview">
                                        <h3>Day: 15</h3>
                                        <table>
                                            <tr>
                                                <th class="regimen-col-2">Medication</th>
                                                <th class="regimen-col-2">Dose</th>
                                                <th class="regimen-col-2">Route</th>
                                                <th class="regimen-col-2">Max duration</th>
                                                <th class="regimen-col-4">Details</th>
                                            </tr>
                                                <tr id="day-details-content|bfe31f90-10e9-4d90-80a2-5aeccec14939-15-1f2b1a9a-5571-40c4-8d62-90a4adb8d23b" title="Cycle 1: alectinib - Day 15" class="regimen-item">
                                                    <td class="regimen-col-2">
                                                        <span title="46490541000116100" class="medication">alectinib</span>
                                                    </td>
                                                    <td class="regimen-col-2 handle-lines">600 mg flat Twice daily</td>
                                                    <td class="regimen-col-2">oral administration</td>
                                                    <td class="regimen-col-2 handle-lines"/>
                                                    <td class="regimen-col-4">
                                                            <div class="regimen-instructions html-instructions"><b>Instructions:</b><br/>Take with food. Swallow whole, do not crush or chew. Protect yourself from too much natural or artificial sunlight while being treated with this medicine.</div>
                                                    </td>
                                                </tr>
                                        </table>
                                    </div>
                                    <div class="day-overview">
                                        <h3>Day: 16</h3>
                                        <table>
                                            <tr>
                                                <th class="regimen-col-2">Medication</th>
                                                <th class="regimen-col-2">Dose</th>
                                                <th class="regimen-col-2">Route</th>
                                                <th class="regimen-col-2">Max duration</th>
                                                <th class="regimen-col-4">Details</th>
                                            </tr>
                                                <tr id="day-details-content|bfe31f90-10e9-4d90-80a2-5aeccec14939-16-1f2b1a9a-5571-40c4-8d62-90a4adb8d23b" title="Cycle 1: alectinib - Day 16" class="regimen-item">
                                                    <td class="regimen-col-2">
                                                        <span title="46490541000116100" class="medication">alectinib</span>
                                                    </td>
                                                    <td class="regimen-col-2 handle-lines">600 mg flat Twice daily</td>
                                                    <td class="regimen-col-2">oral administration</td>
                                                    <td class="regimen-col-2 handle-lines"/>
                                                    <td class="regimen-col-4">
                                                            <div class="regimen-instructions html-instructions"><b>Instructions:</b><br/>Take with food. Swallow whole, do not crush or chew. Protect yourself from too much natural or artificial sunlight while being treated with this medicine.</div>
                                                    </td>
                                                </tr>
                                        </table>
                                    </div>
                                    <div class="day-overview">
                                        <h3>Day: 17</h3>
                                        <table>
                                            <tr>
                                                <th class="regimen-col-2">Medication</th>
                                                <th class="regimen-col-2">Dose</th>
                                                <th class="regimen-col-2">Route</th>
                                                <th class="regimen-col-2">Max duration</th>
                                                <th class="regimen-col-4">Details</th>
                                            </tr>
                                                <tr id="day-details-content|bfe31f90-10e9-4d90-80a2-5aeccec14939-17-1f2b1a9a-5571-40c4-8d62-90a4adb8d23b" title="Cycle 1: alectinib - Day 17" class="regimen-item">
                                                    <td class="regimen-col-2">
                                                        <span title="46490541000116100" class="medication">alectinib</span>
                                                    </td>
                                                    <td class="regimen-col-2 handle-lines">600 mg flat Twice daily</td>
                                                    <td class="regimen-col-2">oral administration</td>
                                                    <td class="regimen-col-2 handle-lines"/>
                                                    <td class="regimen-col-4">
                                                            <div class="regimen-instructions html-instructions"><b>Instructions:</b><br/>Take with food. Swallow whole, do not crush or chew. Protect yourself from too much natural or artificial sunlight while being treated with this medicine.</div>
                                                    </td>
                                                </tr>
                                        </table>
                                    </div>
                                    <div class="day-overview">
                                        <h3>Day: 18</h3>
                                        <table>
                                            <tr>
                                                <th class="regimen-col-2">Medication</th>
                                                <th class="regimen-col-2">Dose</th>
                                                <th class="regimen-col-2">Route</th>
                                                <th class="regimen-col-2">Max duration</th>
                                                <th class="regimen-col-4">Details</th>
                                            </tr>
                                                <tr id="day-details-content|bfe31f90-10e9-4d90-80a2-5aeccec14939-18-1f2b1a9a-5571-40c4-8d62-90a4adb8d23b" title="Cycle 1: alectinib - Day 18" class="regimen-item">
                                                    <td class="regimen-col-2">
                                                        <span title="46490541000116100" class="medication">alectinib</span>
                                                    </td>
                                                    <td class="regimen-col-2 handle-lines">600 mg flat Twice daily</td>
                                                    <td class="regimen-col-2">oral administration</td>
                                                    <td class="regimen-col-2 handle-lines"/>
                                                    <td class="regimen-col-4">
                                                            <div class="regimen-instructions html-instructions"><b>Instructions:</b><br/>Take with food. Swallow whole, do not crush or chew. Protect yourself from too much natural or artificial sunlight while being treated with this medicine.</div>
                                                    </td>
                                                </tr>
                                        </table>
                                    </div>
                                    <div class="day-overview">
                                        <h3>Day: 19</h3>
                                        <table>
                                            <tr>
                                                <th class="regimen-col-2">Medication</th>
                                                <th class="regimen-col-2">Dose</th>
                                                <th class="regimen-col-2">Route</th>
                                                <th class="regimen-col-2">Max duration</th>
                                                <th class="regimen-col-4">Details</th>
                                            </tr>
                                                <tr id="day-details-content|bfe31f90-10e9-4d90-80a2-5aeccec14939-19-1f2b1a9a-5571-40c4-8d62-90a4adb8d23b" title="Cycle 1: alectinib - Day 19" class="regimen-item">
                                                    <td class="regimen-col-2">
                                                        <span title="46490541000116100" class="medication">alectinib</span>
                                                    </td>
                                                    <td class="regimen-col-2 handle-lines">600 mg flat Twice daily</td>
                                                    <td class="regimen-col-2">oral administration</td>
                                                    <td class="regimen-col-2 handle-lines"/>
                                                    <td class="regimen-col-4">
                                                            <div class="regimen-instructions html-instructions"><b>Instructions:</b><br/>Take with food. Swallow whole, do not crush or chew. Protect yourself from too much natural or artificial sunlight while being treated with this medicine.</div>
                                                    </td>
                                                </tr>
                                        </table>
                                    </div>
                                    <div class="day-overview">
                                        <h3>Day: 20</h3>
                                        <table>
                                            <tr>
                                                <th class="regimen-col-2">Medication</th>
                                                <th class="regimen-col-2">Dose</th>
                                                <th class="regimen-col-2">Route</th>
                                                <th class="regimen-col-2">Max duration</th>
                                                <th class="regimen-col-4">Details</th>
                                            </tr>
                                                <tr id="day-details-content|bfe31f90-10e9-4d90-80a2-5aeccec14939-20-1f2b1a9a-5571-40c4-8d62-90a4adb8d23b" title="Cycle 1: alectinib - Day 20" class="regimen-item">
                                                    <td class="regimen-col-2">
                                                        <span title="46490541000116100" class="medication">alectinib</span>
                                                    </td>
                                                    <td class="regimen-col-2 handle-lines">600 mg flat Twice daily</td>
                                                    <td class="regimen-col-2">oral administration</td>
                                                    <td class="regimen-col-2 handle-lines"/>
                                                    <td class="regimen-col-4">
                                                            <div class="regimen-instructions html-instructions"><b>Instructions:</b><br/>Take with food. Swallow whole, do not crush or chew. Protect yourself from too much natural or artificial sunlight while being treated with this medicine.</div>
                                                    </td>
                                                </tr>
                                        </table>
                                    </div>
                                    <div class="day-overview">
                                        <h3>Day: 21</h3>
                                        <table>
                                            <tr>
                                                <th class="regimen-col-2">Medication</th>
                                                <th class="regimen-col-2">Dose</th>
                                                <th class="regimen-col-2">Route</th>
                                                <th class="regimen-col-2">Max duration</th>
                                                <th class="regimen-col-4">Details</th>
                                            </tr>
                                                <tr id="day-details-content|bfe31f90-10e9-4d90-80a2-5aeccec14939-21-1f2b1a9a-5571-40c4-8d62-90a4adb8d23b" title="Cycle 1: alectinib - Day 21" class="regimen-item">
                                                    <td class="regimen-col-2">
                                                        <span title="46490541000116100" class="medication">alectinib</span>
                                                    </td>
                                                    <td class="regimen-col-2 handle-lines">600 mg flat Twice daily</td>
                                                    <td class="regimen-col-2">oral administration</td>
                                                    <td class="regimen-col-2 handle-lines"/>
                                                    <td class="regimen-col-4">
                                                            <div class="regimen-instructions html-instructions"><b>Instructions:</b><br/>Take with food. Swallow whole, do not crush or chew. Protect yourself from too much natural or artificial sunlight while being treated with this medicine.</div>
                                                    </td>
                                                </tr>
                                        </table>
                                    </div>
                                    <div class="day-overview">
                                        <h3>Day: 22</h3>
                                        <table>
                                            <tr>
                                                <th class="regimen-col-2">Medication</th>
                                                <th class="regimen-col-2">Dose</th>
                                                <th class="regimen-col-2">Route</th>
                                                <th class="regimen-col-2">Max duration</th>
                                                <th class="regimen-col-4">Details</th>
                                            </tr>
                                                <tr id="day-details-content|bfe31f90-10e9-4d90-80a2-5aeccec14939-22-1f2b1a9a-5571-40c4-8d62-90a4adb8d23b" title="Cycle 1: alectinib - Day 22" class="regimen-item">
                                                    <td class="regimen-col-2">
                                                        <span title="46490541000116100" class="medication">alectinib</span>
                                                    </td>
                                                    <td class="regimen-col-2 handle-lines">600 mg flat Twice daily</td>
                                                    <td class="regimen-col-2">oral administration</td>
                                                    <td class="regimen-col-2 handle-lines"/>
                                                    <td class="regimen-col-4">
                                                            <div class="regimen-instructions html-instructions"><b>Instructions:</b><br/>Take with food. Swallow whole, do not crush or chew. Protect yourself from too much natural or artificial sunlight while being treated with this medicine.</div>
                                                    </td>
                                                </tr>
                                        </table>
                                    </div>
                                    <div class="day-overview">
                                        <h3>Day: 23</h3>
                                        <table>
                                            <tr>
                                                <th class="regimen-col-2">Medication</th>
                                                <th class="regimen-col-2">Dose</th>
                                                <th class="regimen-col-2">Route</th>
                                                <th class="regimen-col-2">Max duration</th>
                                                <th class="regimen-col-4">Details</th>
                                            </tr>
                                                <tr id="day-details-content|bfe31f90-10e9-4d90-80a2-5aeccec14939-23-1f2b1a9a-5571-40c4-8d62-90a4adb8d23b" title="Cycle 1: alectinib - Day 23" class="regimen-item">
                                                    <td class="regimen-col-2">
                                                        <span title="46490541000116100" class="medication">alectinib</span>
                                                    </td>
                                                    <td class="regimen-col-2 handle-lines">600 mg flat Twice daily</td>
                                                    <td class="regimen-col-2">oral administration</td>
                                                    <td class="regimen-col-2 handle-lines"/>
                                                    <td class="regimen-col-4">
                                                            <div class="regimen-instructions html-instructions"><b>Instructions:</b><br/>Take with food. Swallow whole, do not crush or chew. Protect yourself from too much natural or artificial sunlight while being treated with this medicine.</div>
                                                    </td>
                                                </tr>
                                        </table>
                                    </div>
                                    <div class="day-overview">
                                        <h3>Day: 24</h3>
                                        <table>
                                            <tr>
                                                <th class="regimen-col-2">Medication</th>
                                                <th class="regimen-col-2">Dose</th>
                                                <th class="regimen-col-2">Route</th>
                                                <th class="regimen-col-2">Max duration</th>
                                                <th class="regimen-col-4">Details</th>
                                            </tr>
                                                <tr id="day-details-content|bfe31f90-10e9-4d90-80a2-5aeccec14939-24-1f2b1a9a-5571-40c4-8d62-90a4adb8d23b" title="Cycle 1: alectinib - Day 24" class="regimen-item">
                                                    <td class="regimen-col-2">
                                                        <span title="46490541000116100" class="medication">alectinib</span>
                                                    </td>
                                                    <td class="regimen-col-2 handle-lines">600 mg flat Twice daily</td>
                                                    <td class="regimen-col-2">oral administration</td>
                                                    <td class="regimen-col-2 handle-lines"/>
                                                    <td class="regimen-col-4">
                                                            <div class="regimen-instructions html-instructions"><b>Instructions:</b><br/>Take with food. Swallow whole, do not crush or chew. Protect yourself from too much natural or artificial sunlight while being treated with this medicine.</div>
                                                    </td>
                                                </tr>
                                        </table>
                                    </div>
                                    <div class="day-overview">
                                        <h3>Day: 25</h3>
                                        <table>
                                            <tr>
                                                <th class="regimen-col-2">Medication</th>
                                                <th class="regimen-col-2">Dose</th>
                                                <th class="regimen-col-2">Route</th>
                                                <th class="regimen-col-2">Max duration</th>
                                                <th class="regimen-col-4">Details</th>
                                            </tr>
                                                <tr id="day-details-content|bfe31f90-10e9-4d90-80a2-5aeccec14939-25-1f2b1a9a-5571-40c4-8d62-90a4adb8d23b" title="Cycle 1: alectinib - Day 25" class="regimen-item">
                                                    <td class="regimen-col-2">
                                                        <span title="46490541000116100" class="medication">alectinib</span>
                                                    </td>
                                                    <td class="regimen-col-2 handle-lines">600 mg flat Twice daily</td>
                                                    <td class="regimen-col-2">oral administration</td>
                                                    <td class="regimen-col-2 handle-lines"/>
                                                    <td class="regimen-col-4">
                                                            <div class="regimen-instructions html-instructions"><b>Instructions:</b><br/>Take with food. Swallow whole, do not crush or chew. Protect yourself from too much natural or artificial sunlight while being treated with this medicine.</div>
                                                    </td>
                                                </tr>
                                        </table>
                                    </div>
                                    <div class="day-overview">
                                        <h3>Day: 26</h3>
                                        <table>
                                            <tr>
                                                <th class="regimen-col-2">Medication</th>
                                                <th class="regimen-col-2">Dose</th>
                                                <th class="regimen-col-2">Route</th>
                                                <th class="regimen-col-2">Max duration</th>
                                                <th class="regimen-col-4">Details</th>
                                            </tr>
                                                <tr id="day-details-content|bfe31f90-10e9-4d90-80a2-5aeccec14939-26-1f2b1a9a-5571-40c4-8d62-90a4adb8d23b" title="Cycle 1: alectinib - Day 26" class="regimen-item">
                                                    <td class="regimen-col-2">
                                                        <span title="46490541000116100" class="medication">alectinib</span>
                                                    </td>
                                                    <td class="regimen-col-2 handle-lines">600 mg flat Twice daily</td>
                                                    <td class="regimen-col-2">oral administration</td>
                                                    <td class="regimen-col-2 handle-lines"/>
                                                    <td class="regimen-col-4">
                                                            <div class="regimen-instructions html-instructions"><b>Instructions:</b><br/>Take with food. Swallow whole, do not crush or chew. Protect yourself from too much natural or artificial sunlight while being treated with this medicine.</div>
                                                    </td>
                                                </tr>
                                        </table>
                                    </div>
                                    <div class="day-overview">
                                        <h3>Day: 27</h3>
                                        <table>
                                            <tr>
                                                <th class="regimen-col-2">Medication</th>
                                                <th class="regimen-col-2">Dose</th>
                                                <th class="regimen-col-2">Route</th>
                                                <th class="regimen-col-2">Max duration</th>
                                                <th class="regimen-col-4">Details</th>
                                            </tr>
                                                <tr id="day-details-content|bfe31f90-10e9-4d90-80a2-5aeccec14939-27-1f2b1a9a-5571-40c4-8d62-90a4adb8d23b" title="Cycle 1: alectinib - Day 27" class="regimen-item">
                                                    <td class="regimen-col-2">
                                                        <span title="46490541000116100" class="medication">alectinib</span>
                                                    </td>
                                                    <td class="regimen-col-2 handle-lines">600 mg flat Twice daily</td>
                                                    <td class="regimen-col-2">oral administration</td>
                                                    <td class="regimen-col-2 handle-lines"/>
                                                    <td class="regimen-col-4">
                                                            <div class="regimen-instructions html-instructions"><b>Instructions:</b><br/>Take with food. Swallow whole, do not crush or chew. Protect yourself from too much natural or artificial sunlight while being treated with this medicine.</div>
                                                    </td>
                                                </tr>
                                        </table>
                                    </div>
                                    <div class="day-overview">
                                        <h3>Day: 28</h3>
                                        <table>
                                            <tr>
                                                <th class="regimen-col-2">Medication</th>
                                                <th class="regimen-col-2">Dose</th>
                                                <th class="regimen-col-2">Route</th>
                                                <th class="regimen-col-2">Max duration</th>
                                                <th class="regimen-col-4">Details</th>
                                            </tr>
                                                <tr id="day-details-content|bfe31f90-10e9-4d90-80a2-5aeccec14939-28-1f2b1a9a-5571-40c4-8d62-90a4adb8d23b" title="Cycle 1: alectinib - Day 28" class="regimen-item">
                                                    <td class="regimen-col-2">
                                                        <span title="46490541000116100" class="medication">alectinib</span>
                                                    </td>
                                                    <td class="regimen-col-2 handle-lines">600 mg flat Twice daily</td>
                                                    <td class="regimen-col-2">oral administration</td>
                                                    <td class="regimen-col-2 handle-lines"/>
                                                    <td class="regimen-col-4">
                                                            <div class="regimen-instructions html-instructions"><b>Instructions:</b><br/>Take with food. Swallow whole, do not crush or chew. Protect yourself from too much natural or artificial sunlight while being treated with this medicine.</div>
                                                    </td>
                                                </tr>
                                        </table>
                                    </div>
                            </div>
                        </div>
                </div>
                <div class="references">
                    <h2>Supportive Care Factors</h2>

                        <table>
                            <tr>
                                <th class="regimen-col-3">Factor</th>
                                <th class="regimen-col-4">Value</th>
                            </tr>
                                <tr>
                                    <td class="regimen-col-3">Diarrhoea risk:</td>
                                    <td class="regimen-col-4">Anti-diarrhoeals are usually prescribed with this treatment</td>
                                </tr>
                                <tr>
                                    <td class="regimen-col-3">Emetogenicity:</td>
                                    <td class="regimen-col-4">Minimal</td>
                                </tr>
                        </table>
                </div>
                <div class="references">
                    <h2>References</h2>
                            <p class="regimen-reference">
                                <small>1.	Peters, S., D. R. Camidge, A. T. Shaw, et al. 2017. &quot;Alectinib versus Crizotinib in Untreated ALK-Positive Non-Small-Cell Lung Cancer.&quot; N Engl J Med 377(9):829-838., PMID: 28586279</small>
                            </p>
                            <p class="regimen-reference">
                                <small>2.	Hida, T., H. Nokihara, M. Kondo et al. 2017. &quot;Alectinib versus crizotinib in patients with ALK-positive non-small-cell lung cancer (J-ALEX): an open-label, randomised phase 3 trial.&quot; Lancet 390(10089):29-39., PMID: 28501140</small>
                            </p>
                            <p class="regimen-reference">
                                <small>3.	Camidge, D. R, Rafal D, Solange P, 2019. &quot;Updated Efficacy and Safety Data and Impact of the EML4-ALK Fusion Variant on the Efficacy of Alectinib in Untreated ALK-Positive Advanced Non–Small Cell Lung Cancer in the Global Phase III ALEX Study.&quot; Journal of Thoracic Oncology 14(7):1233-1243., PMID: 30902613</small>
                            </p>
                            <p class="regimen-reference">
                                <small>4.	Roche Products (New Zealand) Limited. Alecensa New Zealand Data Sheet 16 August 2018. https://www.medsafe.govt.nz/profs/Datasheet/a/alecensacap.pdf (Accessed 02 December 2020)</small>
                            </p>

                </div>
                <div class="disclaimer">
                    <p><b>* The medicines, doses, combinations, and schedule in this treatment regimen have been carefully reviewed against international best practice guidelines by specialists in medical oncology around New Zealand and this advice has been accepted for publication by Te Aho o Te Kahu (the Cancer Control Agency). Sometimes medicines that are used in routine clinical practice have not been through a formal review process by the NZ Medicines Regulator Medsafe and are therefore considered unapproved or off-label. These medicines are legally able to be prescribed through sections 25 and 29 of the Medicines Act and by obtaining informed consent from patients. All treatment regimens listed on this website have been through robust peer review and are considered an accepted standard of care, whether prescribed through sections 25 or 29 or carrying formal Medsafe Approval.</b></p>
                </div>
            </div>
        </div>
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